急性心肌梗死患者血清sLOX-1、CK-MB水平及意义

目的探讨急性心肌梗死(AMI)患者血清可溶性凝集素样氧化型低密度脂蛋白受体-1(sLOX-1)和心肌型肌酸激酶同工酶(CK-MB)水平及意义。方法选取AMI患者120例(AMI组),同时选取健康体检者120例作为对照组,检测血清sLOX-1、CK-MB水平。结果AMI组患者血清sLOX-1、CK-MB水平明显高于对照组(P<0.05);AMI组左室舒张末期容积指数(LVEDVI)、左室收缩末期容积指数(LVESVI)和左室射血分数(LVEF)分别为(73.39±2.29)mL/m^2、(38.83±9.28)mL/m^2和(47.88±8.29)%;血清sLOX-1、CK-MB与LVEDVI、LVESVI和LVEF未见明显相关性(P>0.05);AMI组重度狭窄患者血清sLOX-1、CK-MB明显高于轻度和中度狭窄患者(P<0.05);中度狭窄患者血清sLOX-1、CK-MB明显高于轻度狭窄患者(P<0.05);血清sLOX-1、CK-MB与Gensini评分呈正相关(G=0.339和0.252,P<0.05),血清sLOX-1与CK-MB呈正相关(r=0.301,P<0.05)。结论急性心肌梗死患者血清SLOX-1、CK-MB水平升高,与冠状动脉狭窄程度有一定相关性。     

Reappraisal of the Traditional Wenckebach Phenomenon with a Modified Ladder Diagram

Understanding of the traditional Wenckebach phenomenon is enhanced by using a modified ladder diagram where AV conduction in any cycle is represented by a slanted line in the AV bar together with similar AV conduction lines of all the preceding cycles. The diagram facilitates calculation of the duration of RR intervals (equal to the basic PP or sinus interval minus the PR or AV increment applied to this particular cycle) and the duration of the pause (equal to 2 × PP or sinus interval minus the sum of all the increments applied to the AV delay). The modified Wenckebach diagram should help students understand the mysterious clustering of QRS complexes or “paradoxical” increase of the ventricular rate that occurs during a Wenckebach sequence. Ann Noninvasive Electrocardiol 2012;17(1):3–7     

护理学硕士研究生择业效能感的调查研究

正择业效能感,是指个体对于自己实施和坚持与择业相关行为能力的信念[1],是自我效能感在职业指导领域的扩展。近年来,随着护理学高学历教育的崛起,护理硕士研究生数量迅速扩大,不少护理硕士研究生对自身专业特点、就业前景等情况尚未充分了解,包括其就业期望也常与就业形势存在差距,从而导致就业期间出现各种心理冲突及就业不理想等现象。有研究发现择业效能感与个体职业选择有较高的相关性[2],因此,本研究对护理硕士研究生择业效能感进行调查,     

经阴道彩超对子宫内膜癌肌层浸润程度和病理分期的诊断效果研究

目的:探讨经阴道彩超对子宫内膜癌Ⅰ期肌层浸润程度的诊断效果。方法:选取我院2015年收治的子宫内膜癌Ⅰ期患者72例,均进行经阴道彩超检查,分析患者的肌层浸润程度。结果:分级越高的患者肌层的浸润程度更厉害(P0.05),淋巴结转移患者的子宫浸润程度更厉害(P0.05),经阴道彩超筛查子宫内膜癌患者的肌层浸润灵敏度是84.0%,特异度是89.4%,经阴道彩超同病理分期的诊断符合率是72.2%。结论:子宫内膜癌Ⅰ期患者使用经阴道彩超进行诊断的效果比较可靠,并且费用低廉、操作简便,能够为临床上患者的早诊断以及早治疗提供依据,从而改善治疗的效果。     

右美托咪啶联合用药新方案用于重症医学科长时间镇静的研究

目的比较在重症医学科内长时间镇静状态下不同镇静方案的差别，找出较适合长时间镇静的方案。方法选取在我院重症医学科住院的患者80例，随机分为4组，即右美托咪啶持续泵注联合咪达唑仑间断应用组（A组，n=20），右美托咪啶与咪达唑仑联合持续泵注组（B组，n=20），咪达唑仑单独持续泵人组（C组，n=20），右美托咪啶单独持续泵人组（D组，n=20）。镇静目标为肌肉活动评分法（monitor activity assessment scale, MAAS）3分．镇静过程中持续心电监护，监测镇静满意程度，记录4组患者3日用药量变化，并监测患者不良反应发生率。比较4组患者后3种指标的差别。结果A、B两组较C、D两组镇静满意程度显著增高，用药量变化幅度较小，不良反应较少，其中又以A组不良反应为最少，且与B组相比咪达唑仑用药量显著减少。结论右美托眯啶持续泵注联合咪达唑仑间断应用可显著减少长时间镇静所需药物用量．且减少不良反应。     

健康体检育龄妇女阴道分泌物检测结果分析

目的了解健康体检育龄妇女阴道病原菌感染的状况。方法分别于2009年和2010年对344名育龄妇女健康体检人员,检测阴道清洁度、滴虫、霉菌及细菌性阴道病（BV）四项指标。结果 2009和2010年体检结果阴道清洁度异常率分别为37%和29.8%;滴虫感染比率分别为1.7%和0.6%;霉菌感染比率分别为7.5%和9.4%;BV的感染比率分别为40.5%和39.8%。阴道清洁度Ⅲ～Ⅳ度的霉菌感染比率明显高于清洁度Ⅰ～Ⅱ度（χ2=19.11,P〈0.01）。结论不同年度间清洁度、滴虫、霉菌、BV感染率在育龄妇女健康体检人群中分布无明显变化。清洁度异常者霉菌的感染比率高。BV在所有阴道感染中比率最高。     

护理干预对同步放化疗治疗非小细胞肺癌患者疗效及生活质量的影响

目的探讨护理干预对同步放化疗治疗非小细胞肺癌疗效及生活质量的影响。方法均给予本院50例非小细胞肺癌患者同步放化疗治疗,根据随机数字法,将其分为对照组(常规护理)和观察组(护理干预),各25例,比较2组治疗的临床疗效、生活质量评分及护理满意度。结果与对照组相比,观察组治疗的总有效率显著增高(P0.05),观察组护理后生活质量各维度得分及总分均显著增高(P0.05);与对照组相比,观察组患者对护理服务满意度显著提升(P0.05)。结论同步放化疗治疗非小细胞肺癌期间,有效的护理干预能够提高临床疗效,提升患者的生活质量及满意度。     

健康教育对水中分娩产妇影响的研究

[目的]了解健康宣教对产妇水中分娩的影响。[方法]选择2006年10月-2008年4月符合水中分娩条件的46例产妇为实验组，对符合水中分娩的产妇及家属进行水中分娩健康教育，以同期进行传统分娩的产妇61例为对照组。对两组产妇产后的疼痛强度、隐私满意度、体位舒适度及两组活跃期及第二产程时间进行比较。[结果]两组产妇疼痛强度及体位舒适度经比较差异有统计学意义，隐私满意度差异无统计学意义。[结论]在符合水中分娩条件下，通过健康宣教可促进水中分娩顺利进行。     

The transition to practice of Direct Entry Clinical Nurse Leader graduates

This study looks at Direct Entry Clinical Nurse Leader graduates and how their transition to practice experiences develops over time as well as factors influencing their transition. Graduates were surveyed at graduation, three, six and 12 months. Seventeen participated; eight completed all surveys. Most were from the Millennial generation. The survey consisted of two parts: school satisfaction and the Casey-Fink Graduate Nurse Experience Scale. The results showed the Casey-Fink total score at 12 months was 0.75 points higher than at three months; suggesting a positive transition. The highest score occurred at six months which conversely had the lowest levels of satisfaction with both educational experience and intent to stay in their current role. Despite having 850 precepted/mentored clinical hours, 57.1% of these graduates stated they felt unprepared for the reality of nursing after 12 months. Regardless of feeling unprepared, the results suggest these students displayed a positive transition to practice. At 12 months, 88.2% were still with their first employers which contrasted the results of Casey-Fink and other studies of Millennial gradate nurses, which showed higher actual and intent to leave results. This study suggests that Direct Entry Clinical Nurse Leader students do indeed transition to practice more positively than traditional nursing graduates.